Which of the following is NOT listed as a cause of Overactive Bladder (OAB)?

• A. Pregnancy
• B. Metabolic conditions
• C. Inflammation/infection
• D. Neurologic conditions

Answer: (A)

Overactive bladder is driven by factors that alter detrusor muscle activity or bladder sensation, such as neurologic disorders that disrupt neural control, metabolic conditions that affect bladder nerves and function, or inflammatory/infectious processes that irritate the bladder lining. Pregnancy, while it can cause temporary urgency and frequency due to uterine pressure and hormonal changes, is not considered a lasting cause of OAB. These pregnancy-related symptoms typically resolve after delivery, so pregnancy is viewed as a transient physiologic state rather than a chronic etiologic factor for OAB. Therefore, pregnancy is the option that is not listed as a cause.